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- 飞鹰 (3164字节) 1/28 14:57 (93762)


飞鹰:杂交致癌这个想法其实很好,也可能是一个真理,关键的问题是要找到相关的证据。

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送交者: 飞鹰 于 January 28, 2004 14:57:19:

老刘,偶尔的机会看到你的有关杂交致癌的新思想。这个想法其实很好,也可能是一个真理,关键的问题是要找到相关的证据。证据有两方面的,一方面是理论与数学模型,然后是实验证据,得到实验证据很困难(生物医学实验要花多少钱?我想象不到)。从目前的情况来说,第一步是理论与数学模型。民科之所以受到一些人的误解,有你们自身的原因。你如果要让你的发现让科学世界接受,就要进入到科学世界中来,包括把你的发现置于科学的上下文中,利用已有的科学发现,采用科学的语言,关键是引用科学文献。其实已经有一些和你的想法类似的东西,下面的一些科学文献就可以找到一些(还有很多),特别是最前面的三篇,第一篇对人类进化的最新综述,而第二篇是关于昆虫的例子,第三篇是远交衰退的模型。这都是科学文献,将你的发现置于这样一种上下文中,有助于你的想法被科学世界接受。


Human Biology: an Evolutionary Perspective 2003. http://www.isem.univ-montp2.fr/GE/meeting_site/human_biology_fichiers/programHBEP2.pdf

Neel, J.V. (1993) Human consanguinity effects revisited: Why is the measurable impact of inbreeding so small? in Genetics of cellular, individual, family and population variability, (eds. Sing, C.F. and Harris, C.L.) 58-82 (Oxford University Press, New York).

Edmands, Suzanne & Timmerman, Charles C. Modeling Factors Affecting the Severity of Outbreeding Depression. Conservation Biology 17 (3), 883-892.

G. Dwyer, J. Dushoff, J.S. Elkinton, J.P. Burand, S.A. Levin. 2000. Host heterogeneity in susceptibility: lessons from an insect virus. To appear in Virulence Management U. Diekmann, K. Sigmund, M. Sabelis, J.A.J. Metz, editors. Cambridge University Press.

Freire-Maia, N. and Freire-Maia, A. (1961) The structure of consanguineous marriages and its genetic implications. Annals of Human Genetics 25: 29-39.

Hajnal, J. (1963) Concepts of random mating and the frequency of consanguineous marriages. Proceedings of the Royal Society of Ser B
159: 125-177.

Haldane, J.B.S. (1939) The spread of harmful autosomal recessive genes in human populations. Annals of Eugenics 9: 232-237.

Haldane, J.B.S. and Jayakar, S.D. (1962) An estimation of some human relationships. Journal of Genetics 58: 81-107.

Kunstadter, P., Buhler, R., Stephan, F.F. and Westoff, C.F. (1963) Demographic variability and preferential marriage patterns. American Journal of Physical Anthropology 21: 511-519.

Lynch, M. (1991) The genetic interpretation of inbreeding depression and outbreeding depression. Evolution 45: 622-629.

McKusick, K.B., Schach, S.R. and Koeslag, J.H. (1990) Social mechanisms in the population genetics of Tay-Sachs and other lethal autoaomal recessive disease: a computer simulation model. American Journal of Medical
Genetics 36: 178-182.

Morton, N.E. (1955) Non-randomness in consanguineous marriage. Annals of Human Genetics 20: 116-124.


Rogers, A.R. and Jorde, L.B. (1987) The effect of nonrandom migration on genetic differences between populations. Annals of Human Genetics 51: 169-176.

Wendel, T.D. (2000) The beneficial effect of donor-specific transfusions: a review of existing explanations and a new hypothesis based on a relatively unapplied theory of T cell immunoregulation. A regulatory hypothesis in progress. Medical Hypotheses 54: 922-943.




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